So I've noticed that punctuation characters seem to generally not be considered part of the optimisation process here and I found this old post by Shai that explains some of the reasons for this. However I think it might be worth treating ' differently as it is an integral part of standard English prose.
I admit I started down this road because while coding I was picking up a lot of contention on my right pinky around strings in JSON and value assignments:
{'key':'value'}
var='value'
' " [ { + - = _ ; : } ] are all on the right pinky so that's a lot of same finger bigrams. Moving the ' to another position would be the easiest way to provide some relief. Coming from Dvorak the Q was a natural position to consider. Q > ; > ' is a simple rotation that achieves this. After trying this out I think it actually provides a number of benefits.
Some benefits of this rotation are:
QU becomes a nice inward roll on the right hand (eg quick).
't, 's, 'd and 're also become inward rolls on the left hand (eg don't, he's, she'd, we're).
Provides hand alternation in many programming languages where string quoting is likely to be mixed with other punctuation symbols (c='a'+'b').
:q also becomes an inward roll for vim users with using alternative ring-finger fingering on the Q.
O' is also no longer a same finger bigram which should help the Irish and their descendants.
The AQ same finger bigram (eg aquarium) is replaced by OQ (soliloquy) but I would guess that these are both pretty rare and this is a neutral change.
All characters stay on the same finger with Q and ' only swapping hands.
I've been using this for a couple of days now and the most uncomfortable sequence I've found is 're and while it's not technically a same finger bigram, I find it a bit too close to hit comfortably but perhaps that will improve with practice.
I know this is two additional switches from QWERTY but other than that I don't see much downside. Is there anything I am missing? While the benefit will be greatest for programmers, there still seem to be plenty of other benefits for normal English prose to make it worth considering.