There are always problems with different languages. Layouts are optimized for a specific language and rarely for several of them at one time. Thankfully, Colemak suits my Lithuanian needs very well (maybe except J letter, because its has average frequency, not the least as its in English. And also, we do not use qwx - luckily, those letters aren't in the best places). As for Indonesian, maybe there are special layouts for your language? Your country is way bigger than mine, so there must be specialists who work on this subject.

I suspect that in most cases there isn't enough to be gained from switching major key positions around to make it worth the while. Even a radically higher A frequency doesn't sound enough to me - after all, it's on the home position and not hidden away on some stretch! Here in Norway we use R a whole lot and its Colemak position works just fine for me. Pinkies and ring fingers aren't so bad, if they don't have to stretch anywhere.

Qwertie, you have a good point about the latin roots. English even fits Germanic languages well enough, with plenty of common heritage in that department as well.

Special signs is a different matter. But they're hardly ever in the very common category so in most cases they fit just fine on keys that the US layout uses for punctuation - such as [].

Then, there's the fact that most of us type some English too. How much varies from person to person, so you'd have to optimize individually. Come to think of it, we even tend to talk about different things, at least some of us do. You might be able to optimize a layout for X-Box-fixing X-ray experts with exasperating ex-sexpartners I guess, by optimizing from a personal corpus. I think that's an exercise for the not easily vexed.  ;)

Pepoluan, no advertisements please!

Another comment for Colemak: For years I've been avoiding working using notebook because the cramped keys in QWERTY layout hurt my fingers. I always choose to work on desktop with an ergonomic keyboard and in my view, I can only use notebook with at least 13.3" wide screen since the width can accomodate fuller size keyboard. Now I'm happily type on a 12.1" normal width notebook since I'm using Colemak layout. Although I type mainly in Bahasa Indonesia, and perhaps only 30% in English, it's still better than QWERTY because the 'A' key which is very often used in Bahasa Indonesia is paired with 'Q', 'Z' and 'X' which is very rarely used, so the load on pinky finger is not to heavy.