It's easy to get better home row usage! Minimak is the extreme example of that. But what you want in a decent layout is more. Same-finger digraphs are bad, for instance. Digraphs in general should be your concern, not only crude monographs.
If you are a home row (or more precisely, home position) fanatic and in addition type exclusively in English then you may notice that not everything is completely optimal for you in Colemak. The H is relatively common and could've been moved in to the home position, and the A may be considered too common for the left pinky. But considering the most frequent letters in English are (more or less) ETAOIN SHRDLU, they have all gotten decent placements in this layout. And considering all the other factors you should consider, I'd say it's hard to beat Colemak for a balanced approach. Not impossible, but hard. Many have tried and are hardly heard of anymore.
All in all, there's probably always a layout or ten that's better for you since your preferences and needs will vary from others'. But it may be hard to find and probably isn't invented yet. So you could use an algorithm to try and find it? But I don't trust those algoritms because their underlying models are oversimplified and sometimes dead wrong because the assumptions of their makers are wrong. So the only good test would be to make a layout and use it for a long time and then wash rinse repeat - and that's not easy to do! Some have done it but there's always the question of what's a long enough trial period and how biased you are based on your prior knowledge and preferences etc etc. And in the end you'll end up with a layout that's best for you, but not necessarily for many others. Fun, huh? ;)
Colemak. It's damn good. It fits lots of people's needs. It doesn't require that you carry around your own keyboard. It's got good support and several technical solutions supplied by its user mass. And it's there already.
Last edited by DreymaR (25-Aug-2012 07:13:28)