I like the Extend mapping idea. I used to have multiple 'layers' (really just used modifiers) for mousing and shortcuts using Autohotkeys. However, my work computer was 'locked down', so I have to use hardware solutions, except for vbscript and vba.

I use an X Keys 12 switch interface with StealthSwitch FS-1 pedals for left and right mouse movements, and a Stinkyboard for tab, enter, and pgdn. I also use the X Keys at home for pgdn. These pedals are great - I literally couldn't work without them for any length of time.

I had until recently been using a Kinesis Advantage for 2 years. I remapped the keypad layer to the left, navigation and some function keys to the right, and macros (activated with modifiers) on the home row. I stayed in 2nd layer and used a foot pedal to switch to letters when needed. Unfortunately, the pedals are quite stiff, and the board is too tall and large  for my desk - otherwise a good setup.

The computer will not recognize a flash drive, but does accept HID devices. I have access only to approved vendor sites, limited email, excel, our proprietary system, and notepad - even right click is gone :/ from many places. I suspect IT overlooked vbscript or it would be gone.

Perhaps what I miss most is being able to mouse from home row. Mousekeys is not an option, as it is gone too.

Sounds like it's time to polish up the ol' resume.

There are 4 layers. The 2nd - 4th can be programmed, but the 1st can't. Programming is fairly straightforward, but a slight bit clunky.

There is a dip switch for Colemak and Dvorak, but I haven't tried it. I did use a dipswitch option to move the fn key to spacebar, then manually remapped one of the layers.

The layout actually isn't that bad, but a real embedded numpad would be better. I may just require more practice, though.

The board can be remapped to almost anything manually (a few fn layer keys are fixed).

What I most like is the number of levels. I can have a layer for normal text, one for my work's propriety software, and an Excel layer with lots of macros. Not trying to be a commercial for Pok3r - but I do like it.

You would have to remap one of the additional 3 layers. I imagine it's quickest to use the dip switch to convert to regular Colemak and then manually remap that. I didn't use the dip switch simply because I didn't want to possibly upset the macros I'd already made while practicing with the board.

Another good feature is that each layer has an independent fn layer - there are 3 programmable layers each with a programmable fn layer.

As far as my layout goes I'm going to move the 'spacebar' function to a foot pedal. I'm still keeping the actual large key as 'fn'.