As an intensive command line UNIX user, I use the modifier keys (esp. Control), a lot. My pinkies are suffering from this (the so-called Emacs Pinky Syndrome, even though I'm no emacs user), and more and more often I'm really feeling pain at the end of the day.
I got really interested when I looked into ergonomic keyboards like the Kinesis where the modifier keys (Ctrl, Shift, Alt) are pressed with the thumbs. But these keyboards are expensive (although I'd still consider them), and more problematically, very hard to get in Europe (Belgium). Some people have created home-brewed alternatives, but that's an example I'm not going to pursue, especially not at work. :-)
Another alternative I looked into are keyboard pedals like again the ones from Kinesis, but they are also hard to get outside the US.
One ergonomic keyboard that is both affordable and easily available worldwide is the Microsoft Natural Ergonomic 4000 keyboard, which I've read good things about, even on this forum. Although I'm no Microsoft fan, I wouldn't mind buying hardware from them if it's indeed good. But although this keyboard aims to improve wrist positioning, it still uses standard modifier keys placement, so I don't think it would help my "Emacs pinkies".
Anyone with similar experiences and perhaps suggestions?