It's been almost a year now since I decided to switch to Colemak after trying and getting frustrated with Dvorak. For the record, I didn't like Dvorak for the exact reasons stated here, primarily that freaking S and L were placed on the pinkie. Whose idea was that, anyway?
I've typed QWERTY since 1994, and in an effort to do this as quickly as possible, I basically switched cold-turkey. Oh, I fiddled with it for a while so that work was QWERTY and home was Colemak, but that seemed to just be confusing my muscle memory because the two are so similar (especially regarding the position of S, G, D, and F.) So that was it, it was time to just bite the bullet and go nuts.
I printed out the layout and taped it below my monitor until I had it basically memorized, and then I just kept getting faster until tests (gtypist) suggests my speeds have returned to my QWERTY levels (90ish). My burst speed is still a little lagging (105-ish) but my sustained speeds are generally faster without the wrist pain when I really went nuts with QWERTY, so overall, I'm pleased.
Plus, it makes a great security device since I kept my old key-caps! Muahahaah!
I've posted another thread in the "Technical" section because I have some major gripes along the way, but at least I can type again. Heh.